Kenny Dalglish gets his first win as Liverpool boss, while United hit Birmingham for five with Arsenal keeping up the pressure with a home win at Wigan.
Manchester United return to the top of the Premiership following their 5-0 demolition of Birmingham City at Old Trafford.
The Bulgarian magician Berbatov was in exquisite for United, and he opened the scoring after just two minutes. Berbatov added his, and United’s second on the half hour, before Giggs’s sublime finish on the stroke of half time.
Berbatov got his hat trick on in the 53 minute taking his tally to 18 for the season, before Nani made it five and sealed victory for United in the 76 minute.
In the early kick off of the day, Kenny Dalglish celebrated his first win as new Liverpool boss as his team ran out 3-0 winners against Wolves at Molineaux.
Liverpool took the lead through Fernando Torres in the 36 minute, but the Merseyside team did not have everything their own way and were fortunate to go in at half time ahead.
Liverpool came out strong in the second half and Meireles got his second in as many games, before Torres finished Wolves off right at the death.
Arsenal kept the pressure on United after Van Persie hit a hat trick to give them a 3-0 victory at home to Wigan.
The Dutchman opened the scoring in the 22 minute, and struck again in the 58, and 85 minutes in the second half.
Tottenham lost ground in the title race after they were forced to battle back to claim a draw at Newcastle. Coloccini opened the scoring for the home side, before Lennon netted right at the death to rescue a point.
Sunderland began life after Darren Bent with a 2-1 victory away to Blackpool. Kieran Richardson bagged both girls for the Black Cats, with the popular Charlie Adam pulling one back for the Seasiders.
Everton battled for a 2-2 home draw with West Ham. The Hammers went 1-0 right before the half hour through Jonathan Spector. Everton brought it back to 1-1 on 77 through Bilyaletdinov, before Piquionne put West Ham back in front.
Seamus Coleman missed a sitter for the home Side, but Bilyaletdinov struck again to spare the Irish man’s blushes.
Fulham ran out 2-0 winners at home to Stoke thanks to a double strike from Clint Dempsey. The American opened the scoring in the 33rd minute, and got his double from the spot after 56 minutes.